The EFB (European Federation of Biotechnology) Section on Microbial Physiology is now pleased to announce the next meeting in the series "Recombinant Protein Production", hosted by the University of Natural Ressources and Applied Life Sciences:

We thank our sponsors:

Recombinant protein production remains a central component of many biotechnological projects. In some projects the protein itself is the end product, for example as a biocatalyst for industrial scale chemical synthesis, for environmental clean-up, or as the active component of a biological
detergent. In such applications, cheap end products must be generated on a scale large enough to
be financially viable. At the other extreme, high quality protein is required for therapeutic use,
or as the starting point for NMR or X-ray crystallographic structure determination, which is a
prerequisite for rational drug design or for understanding the biology underlying a process.
Quality rather than quantity or production intensity now becomes the over-riding requirement.
The most profitable sector of biotechnology coincides with activities most acceptable to public
perception: the generation of antibodies for use in healthcare ranging from improved diagnosis
to the treatment of chronic disease. The value of the world market of the therapeutic antibodies
sector alone is predicted to expand to $30 billion by 2012, making antibody production a prime
target for fundamental research.

Although bacteria remain attractive hosts in which to produce simple proteins, many mammalian
proteins require extensive post-translational modification that bacteria cannot yet accomplish.
The host strain used for protein production therefore depends critically on both the target protein,
and its intended use. CHO cells and various yeast strains are often used in preference to
bacteria, but there have been exciting recent advances in the development of effective bacterial
glycosylation systems that can be combined with bacterial recombinant protein production.
Whatever the choice, productivity depends critically on the physiology of the host. The
meeting will therefore include such topics as cell nutrition, stress responses, protein folding,
protein secretion, and genetic stability.

By February 2011 it will have been more than two years since progress in this extremely important
field has been reviewed. Each of the last three meetings has been over-subscribed, so some
colleagues were disappointed at being unable to participate. To enable as many people as
possible to attend, we are holding the next meeting in the series in the beautiful city of Vienna
where abundant hotel accommodation is available to suit all pockets. You are warmly invited to
register for this exciting meeting organised by the EFB.

This website will provide you with general information about the conference, details about accomodation and venue as well as about how to submit abstracts and posters.

Online registration for the conference (including online payment) is available on our homepage.

All interested Sponsors can find detailed information here.

For any further information please contact This e-mail address is being protected from spambots. You need JavaScript enabled to view it